In this episode recorded live at TechCrunch Disrupt 2025, TechCrunch Editor-in-Chief Connie Loizos speaks with Vinod Khosla about entrepreneurship in the age of AI and the massive disruptions ahead. Loizos and Khosla discuss why he believes every job is a startup opportunity, his investment thesis of building AI workers rather than tools, and first and foremost why he challenges entrepreneurs to imagine their companies in 2030.
Khosla also talked about his prediction that the rate of extinction of Fortune 500 companies will triple by 2035, the controversial idea of sharing corporate wealth through a national pool, and why he thinks we will have a highly deflationary economy with free health care, education, and legal services.
It also covers his early bet on OpenAI, the AI-climate collision process (which he disputes), his investments in nuclear fusion and ultra-hot geothermal energy, and why the Trump administration's immigration policies represent the “worst possible damage” to American innovation.
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